Resumen

ESCOBAR MENDEZ, MARIA INÉS  y  CARRION, MAYERLY. Estudio "in vivo" de la actividad hipolipemica de la opuntia ficus indica (tuna) en ratones. Univ. Cienc. Soc. [online]. 2011, n.4, pp. 5-12. ISSN 8888-8888.

The cholesterol-lowering effect of Opuntia ficus indica was experimentally demonstrated in vivo in mice during the months of January to June 2009. The average value of cholesterol of 92 mg /dl was obtained from mice understudy in the first week, the second week 106 mg /dl, the third week 105 mg / dl, and the fourth week 102 mg / dl, thus providing a range cholesterol between 92mg/dl and 106mg/dl. Cholesterol was raised endogenously reaching an average of 111.78 mg / dl. With Lovastatin Lipitor, the level fell to 76.86 mg / dl, with the extract of prickly pear; the level fell to 57.34 mg /dl. The triglyceride during the first week was 104 mg /dl, the second week 100 mg / dl, the third week 97 mg / dl, and finally the fourth week was 99 mg / dl, giving a range of triglycerides in mice between 97mg/dl and 104 mg / dl. The endogenously elevated triglyceride had a final value of 103.24 mg / dl. With reference Lovastatin triglyceride levels decreased to 75.52 mg/dl. With the extract of prickly pear, the level fell to 54.96 mg/dl. The weight of the mice had an average of 39.3 grams; the first week after being overfed their average weight was 42.5 grams, the second week with 45.3 gr. With atorvastatin the weight of the mice was reduced from 40.4 gr, to 38.4 gr the first week and 36.6 grams second week, with the prickly pear extract the weight loss was from 48.6 gr, to 41.2 gr the first week and finally 33gr the second week

Palabras llave : Tuna; Opuntia Ficus Indica; Lipid-lowering effect; Mice.