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Revista de Actualización Clínica Investiga
versão impressa ISSN 2304-3768
Resumo
TORRES CAMACHO, Vanesa e ALI PAZ, Griselda Ivonné. Metabolismo de proteinas. Rev. Act. Clin. Med [online]. 2014, vol.41, pp. 2137-2141. ISSN 2304-3768.
Proteins are high molecular weight polypeptides, and its name was given by the union of more than ten amino acids of large structural diversity. Their production by the body is achieved by proteins derived from exogenous dietary and endogenous body's own proteins, both dependent physiological metabolically active and basal levels respectively. Protein metabolism, involves its degradation of proteins, in tripeptides, dipeptides and free amino acids by the action of proteolytic enzymes throughout the gastrointestinal tract, to pass after that into the enterocyte and eventually into the portal system to the liver, in which an amino acid is transported into the bloodstream or is subjected of catabolism. Amino acids are catabolized only when the amount of protein required by the body is exceeded, forming ammonia as a result of oxidative deamination of glutamate. the resulting ammonia is a toxic element for the central nervous system, so its removal should be effective in three ways: synthesis of urea, glutamine formation by extrahepatic organs and renal excretion through the urine.
Palavras-chave : Metabolism; Protein; Amino acid; Urea.