Resumen

CALLISAYA, Juan  y  CATACORA, Virginia. Sodium  hypochlorite  method validation for the diagnosis of lung tuberculosis. BIOFARBO [online]. 2008, vol.16, n.1, pp. 54-60. ISSN 1813-5363.

In order to validate the concentration method with hypochlorite of sodium for the diagnosis of lung tuberculosis, in contrast with the conventional sputum smear and the concentration technique with NaOH, a prospective study was carried out, consisting of 108 samples of sputum, outside and inside a target hospital. The Lowenstein - Jensen cultivation method was used as a reference test. The 108 samples were cultivated and analyzed at the same time by the Sputum Smear methods, and the results were 48 positive and 60 negative. The concentration technique with hypochlorite of sodium presented a sensibility (Sen) of 99.9% and a specificity (Esp) of 86.7%, with a Positive Predictive Value (PPV) of 85.68% and Negative Predictive Value (NPV) of 99.9%, the reason of positive verisimilitude (RPV) and reason of negative verisimilitude (RVN) being respectively  7.50 and 0.00, and finally, the Younden index was 0.87. The concentration method with NaOH presented a Sen of 89,58%, Esp of 99,9%, the VPP was 99,89, the VPN was 92,31, the RVP and PVN were respectively 895,8 and 0,10. The concentration method with hypochlorite of sodium is a sure, economic and quick method that contributes advantages to clinical practice because of its high rates of effectiveness, and its association to the conventional techniques for diagnosis, offers an appropriate diagnosis of lung tuberculosis

Palabras llave : Basiloscopy; Sodium hypochlorite; Sodium hydroxide.