Resumen

CLAROS P., Maysa et al. Actividad anti-Helicobacter pylori de Plantago major, Clinopodium bolivianum, Caléndula officinalis y Piper angustifolium por el método de difusión de disco. BIOFARBO [online]. 2007, vol.15, n.1, pp. 37-42. ISSN 1813-5363.

Helicobacter pylori is a bacteria associated with gastric pathologies such gastritis, ulcers, cancer and MALT lymphoma. According to previous studies in La Paz - Bolivia, approximately 50 % of the population is infected with this bacterium. Bolivia is considered one of the most important countries due to its extensive medicinal plants. The present study evaluates the antibacterial activity of organic and aqueous extracts of Plantago major (Llantén), Clinopodium bolivianum (Khoa), Calendula officinalis (Calendula) and Piper angustifolium (Matico) against Helicobacter pylori. Dichloromethane-, Hydroalcoholic- and aqueous- extracts were tested using the Disk diffusion method with 4 wild-type strains of Helicobacter pylori isolated from biopsies of patients with gastric pathologies. The activity of the extracts was determined according to the diameter of the halo of inhibition. Dichloromethane, Hydroalcoholic and aqueous extracts of Clinopodium bolivianum, Calendula officinalis and Piper angustifolium were found active anti-Helicobacter pylori. Similarly, the hydroalcoholic extract of Plantago major.

Palabras llave : Activity anti-Helicobacter pylori; Plantago major; Clinopodium bolivianum; Calendula officialis; Piper angustifolium.