Resumen

NAVIA BUENO*, María del Pilar et al. Bleedingand metabolic syndrome residents high altitud, La Paz - Bolivia. Cuad. - Hosp. Clín. [online]. 2016, vol.57, n.3, pp. 41-51. ISSN 1652-6776.

Abstract Objective: The aim of the study was to determine if it is a factor of risk the metabolic syndrome for trombóticos and/or alterations in the of platelets, volume (VPM), plaquetocrito (PCT), wide's platelets distribution (ADP), time ofbleeding and time of coagulation in population inhabitant of high altitude 3600 m.s.n.m. to 4100 m.s.n.m. Methods: It is analytical study prospective cohort. The population of study was composed by subjects diagnosed with and without metabolic syndrome in resident population of the high altitude city of La Paz and El Alto (Bolivia) with selection criteria. The calculation ofsample forstudies of prospective Cohort, belonged 291 patients of which 97 are exposed and 194 not exposed ones. Exposed adults, residents of La Paz or El Alto and expire with 3 criteria of metabolic syndrome according to the updated NCEP-ATPIII. They were excluded to persons by physical or mental disability, pregnant women, with diagnosis already defined of cancer and present in treatment with anticoagulants. There were in use instruments validated for the compilation of information, the clinical History, as well as pre-analytical, analytical and pos-analytical procedures in hematology and blood biochemistry, for this end there took a sample of blood of 15 ml. Results: The distribution of demographic and physical variables, in males and exposed women (Sd. Metabolic) and not exposed (without Sd. Metabolic), sample differentiaes significant statics. The hematologic and biochemical variables, they present values p not significant, in mean platelets volume (VHP), plaquetocrito (PCT), wides platelets distribution (ADP).

Palabras llave : Metabolic syndrome; platelet; coagulation and high altitude.