Resumo

MAMANI, Josue¹ et al. Evaluation of genotoxic risk due to shoe polish exposurein shoeshine boys. La Paz-Bolivia. Cuad. - Hosp. Clín. [online]. 2016, vol.57, n.3, pp. 17-24. ISSN 1652-6776.

Abstract Objective: To asses the genotoxic risk in shoeshine boys who are constantly exposed to shoe polish and its components. Material and methods: The study was cross-sectional (exposed and controls) and of cross over trials. It was studied 53 shoe shiners (exposed group) and 24 controls. The buccal cytome technique was applied on children for determining genotoxic damage. Results: The average age of the exposed group and controls was 35.0 ±8.8 and 27.8 ± 1.5 respectively. The exposed group consisted males (83%) and women (17%), with an average of 13.4 years of work ± 7.6, most of which do not use labor protection measures (73.6%). No significant differences were observed in frequency of metanucleadas alterations from the group of exposed and controls: binucleate (BN) (p = 0.273), broken egg (BE) (p = 0.635), karyorrhexis (KR) (p = 0.677), karyolysis (KL) (p = 0.770), cellular repair rate (RR) (p = 0.201). The analysis of association between exposure and genotoxicity showed that the use of shoe polish and its components is not a risk factor. The assessment pre and post-exposure to shoe polish in the exposed group showed no significant differences after the window period for BN (p = 0.804), BE (p = 1.274), CR (p = 0.503), CL (p = 1.000) and RR (p = 0.424). Conclusion: The use ofshoe polish by shoeshine boy population is not a genotoxic risk factor. However it is necessary to continue cohort studies with a larger population.

Palavras-chave : Shoeshine boy; micronucleus; rate of cell repair; cytotoxicity.