Resumo

RAMOS MOLLINEDO, Mabel Freysi. Action precancerigena of the trans isomers of fatty acids and molecular alterations in cellular metabolism. SCIENTIFICA [online]. 2013, vol.11, n.1, pp. 7-13. ISSN 1813-0054.

ABSTRACT The consumption of trans isomeric fatty acids (TFA) in developed countries is well established, and almost all of them have proposed policies and regulations aimed at the drastic reduction in the presence of trans isomers in manufactured foods. Reduction processes of AGT through hydrogenation and transesterification, although they involve a substantial reduction of the AGT, they also produce an increased content of fatty acids Cancer is a leading cause of death in Western countries. Among the factors contributing to the onset of the disease, diet plays a key role, specifically, fat is the main component related to the increase in the incidence of cancerous diseases, especially breast, colorectal , and stunned prostate cancer, which are equally or more harmful to health than AGT. The dietary lipids are particularly associated with breast, prostate and colon-rectum, and between them, the mammary tumurogénesis has, until now, the most extensively studied having a carcinogenic action trans isomers of the fatty fatty.

Palavras-chave : unsaturated fatty acids; trans isomers; metabolism; carcinogenicity.